| Published July 1, 2025

Alligator presents 24-month data from OPTIMIZE-1

Alligator Bioscience presents updated data from the OPTIMIZE-1 study with the CD40 agonist mitazalimab vid ESMO Gastrointestinal Cancers Congress July 2–5 in Barcelona. Patients with metastatic pancreatic cancer treated with 900 μg/kg mitazalimab showed a median survival of 14,9 months and a two-year survival of 29,4 percent. The response rate was 54,4 percent for the higher dose compared to 22,7 percent for 450 μg/kg. The FDA has confirmed 900 μg/kg as the recommended dose for phase III.