| Published June 13, 2025

BioArctic advances phase IIa study with exidavnemab

BioArctic announces that exidavnemab demonstrated good safety and tolerability in the first cohort of the Phase IIa EXIST trial for Parkinson's disease. Following positive safety evaluation, two additional cohorts with higher doses are now being initiated for both Parkinson's disease and multiple system atrophy (MSA). The study is evaluating safety, pharmacokinetics and biomarkers for slowing disease progression by targeting aggregated alpha-synuclein.